treatment should not breastfeed their infants see Use in Specific Populations (8.2). Limit pravastatin to 20 mg once daily for concomitant use with cyclosporine see Dosage and Administration (2.6), Warnings and Precautions (5.1), and Clinical Pharmacology (12.3). Laboratory Test Abnormalities Increases in ALT, AST values and CPK have been observed see Warnings and Precautions (5.1,.2). Because of the potential for serious adverse reactions in a breastfed infant, advise patients that breastfeeding is not recommended during treatment with Pravachol. Crouse JR, Byington RP, Bond MG,. Bottles contain a desiccant canister. Compared to healthy subjects with normal renal function, patients with severe renal impairment had 69 and 37 higher mean AUC and Cmax values, respectively, and.61 hour shorter t for the inactive enzymatic ring hydroxylation metabolite (SQ 31,945). If an alternate etiology is not found do not restart Pravachol. See Warnings and Precautions (5.2). Table 6: care - Primary and Secondary Endpoints Number of Subjects Event Pravastatin 40 mg (N2081) Placebo (N2078) Risk Reduction p-value a The risk reduction due to treatment with Pravachol was consistent in both sexes.
Pravachol Drug Interactions
Cardiovascular deaths were decreased by 32 (73 vs 50,.03) and there was no increase in death from non-cardiovascular causes. Hyperlipidemia, pravachol is indicated: as an adjunct to diet to reduce elevated total cholesterol (Total-C low-density lipoprotein cholesterol (LDL-C apolipoprotein B (ApoB and triglyceride (TG) levels and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and. Dark urine, yellowing of the skin or eyes ( jaundice while talking Lipitor, there is a possible risk of myopathy, a muscle disease in which the muscle fibers do not function properly. Click on "Free Coupon" below and sign up to get your free SingleCare kia coupons pharmacy savings card. Lactation Pravastatin is present in human milk. For dosing information see Dosage and Administration (2.4). Minor, minimally clinically significant. Limitations of Use, pravachol has not been studied in conditions where the major lipoprotein abnormality is elevation of chylomicrons (Fredrickson Types I and V).
Reduce the risk of stroke and stroke/transient ischemic attack (TIA). A total of 170 drugs (488 brand and generic names) are known to interact with. Pediatric Patients Children (Ages 8 to 13 Years, Inclusive) The recommended dose is 20 mg once daily in children 8 to 13 years of age. Based on urinary recovery of total radiolabeled drug, the average oral absorption of pravastatin is 34 and absolute bioavailability.